Case Study: Applied Genetic Modification

Dr. Charlie Arntzen, a leader in the development of edible vaccines, has suggested that only 125 acres of transgenic plants might produce enough edible hepatitis B vaccine to immunize all of China. The cost of administering this vaccine would be pennies.

In this case study, we’ll see how to generate a plant that produces a hepatitis B protein for potential vaccine use. Along the way, we’ll examine in detail the use of restriction enzymes for cloning and plasmid mapping. These techniques have many molecular biology applications, from mapping and cloning human genes, to obtaining DNA for evolutionary comparisons.

The menu to the right has an outline of this case study, with links to the key steps.

Click CONTINUE to begin the case study by choosing a plant system.

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