Unit 6.5 History: Nobel Laureate
Prof. Linus Pauling received the Nobel Prize for Chemistry
in 1954, for his work on the nature of chemical bonds and
the structure of molecules and crystals. He also received
the Nobel Peace Prize in 1962. Video program cues: 33:10-35:50
About Prof. Linus Pauling
- The Nobel
Prize in Chemistry. Click on links to see Pauling
biography and his Nobel acceptance speech.
Prize information about Pauling with links to other
sources about him.
Davenport, D.A., (1996)' reviews: The Many Lives of Linus
Pauling: A Review of Reviews, 'Journal of Chemical Education,
Vol. 73, No. 9, pp: A210.
The discovery of protein folding
"I built so many models by 1948, that
I could start to do it in my head, or just on a sheet of
paper. Whats wrong about this plane, in the structure
I put here [protein structure] is that the angle between
these two bonds is 1800. But it ought to be 109.470,
the Tetrahedral Angle
I dont think I got any
smarter by 1948 than I was in 1937, I didnt know anything
new, but I said suppose that all of these residues are equivalent
to one another. I knew then, that the structure that they
would have had to assume would have been that of a helix."
Professor Linus Pauling
Bowen, R., Hartung, R., Gindt, Y. M. (2000)' A Simple Protein
Purification and Folding Experiment for General Chemistry
Laboratory, 'Journal of Chemical Education, Vol.
77, No. 11, pp: 1456-1457.
to Unit 6.6