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Interactives -- DNA

Human Genome : The Sequencing Effort
 

Although sequencing methods have improved, they can still handle no more than a thousand bases at a time, which doesn't even come close to the 22,700,000 bases of the Y chromosome, the smallest in our genome. That's why scientists had to break apart the genome into much shorter sequences, which were then processed and sequenced.

Two major groups raced to be the first to finish sequencing the human genome, and each used a different method to break apart the genome prior to sequencing. The first group, a publicly funded consortium with efforts coordinated by the United States Department of Energy and the National Institutes of Health and sequencing done at labs around the world, decided to sequence the individual chromosomes by breaking them down into many consecutive shorter parts, which were then read in order.




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